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Correspondence |
Surrey Border Partnership Trust and Honorary Lecturer, St Georges, Univeristy of London, Cranmer Terrace, London SW17 0RE, email: rmukherj{at}sgul.ac.uk
Division of Clinical Developmental Sciences, St Georges, University of London
Shah & Howard (Psychiatric Bulletin, August 2006, 30, 294297) investigated smoking and substance misuse in pregnant women with mental illness. We are concerned about the interpretation of their data and the lack of adequate accounting for confounding factors.
Our recent review highlighted that the timing and level of alcohol consumption in pregnancy was important to outcome (Mukherjee et al, 2006) but this was not taken into account by Shah & Howard. It would have been better to divide the alcohol consumption group into no alcohol, previous alcohol and ongoing alcohol consumption in order to exclude it as a confounding effect. Since 61% of the population has been shown to drink during pregnancy, and there is a large underestimate of consumption, it is a risk factor that must be adequately excluded.
This publication potentially challenges data emerging from international literature. Here the small numbers in some of the subgroups, combined with the failure to control adequately for the important risk factor that is alcohol, means that an otherwise important piece of research will have to be interpreted with caution.
References
MUKHERJEE, R. A. S., TURK, J. & HOLLINS, S. (2006)
Fetal alcohol spectrum disorder: an overview. Journal of the Royal
Society of Medicine, 99, 298
302.
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