The Psychiatrist (2007) 31: 293-294. doi: 10.1192/pb.bp.106.012963
© 2007 The Royal College of Psychiatrists
Improving prescription quality in an in-patient mental health unit: three cycles of clinical audit
Priti Ved, Clinical Pharmacist
Coventry Teaching Primary Care Trust, The Caludon Centre, Coventry
Tim Coupe, Clinical Audit/Effectiveness Officer
Coventry Teaching Primary Care Trust, The Caludon Centre, Clifford Bridge
Road, Coventry CV2 2TE, email:
tim.coupe{at}uhcw.nhs.uk
Declaration of interest
None.

Abstract
AIMS AND METHOD
We undertook three cycles of clinical audit of prescription charts to
improve the quality of the prescriptions written in an in-patient unit.
Pharmacy and medical staff reviewed a total of 1466 prescriptions on 242
prescription charts against local guidelines and provided feedback to medical
staff. The pharmacist also regularly reviewed prescription charts on the wards
between audits.
RESULTS
After three cycles of audit, 99.5% of prescriptions written were legible.
The recording of drug allergies, section 58 status and patient age remained
poor.
CLINICAL IMPLICATIONS
A combination of clinical audit and continual pharmacist review of
prescription charts can improve the quality of prescriptions written by
medical staff in an in-patient unit.

Introduction
Prescription writing is a basic clinical skill for all doctors,
but errors
in prescriptions are believed to be one of the most
common forms of medical
error. Prescription errors may lead
to harm in a number of ways, including
sub-therapeutic dosage,
potential overdose or unintended polypharmacy. This
type of
error may occur for a number of reasons: some relatively complex,
such
as short-comings in medical training, and others more
mundane, such as
fatigue, interruptions, or being asked to
cover unfamiliar patients
(
Dean et al, 2000).
One study of
prescriptions in a psychiatric unit for older people found that
20% were illegible and one-third contained missing information
(
Nirodi & Mitchell, 2002).
Clinical audit is a commonly
used quality improvement process which measures
clinical practice
against agreed standards and introduces change where this is
indicated (
National Institute for Clinical
Excellence, 2002).
Coventry Teaching Primary Care Trust published
guidelines for
the completion of prescriptions in May 2001. We used a series
of clinical audits in the period June 2001 to February 2006
in an attempt to
improve the quality of prescriptions written
at the Caludon Centre, a 70-bed
in-patient unit in Coventry.

Method
A prospective clinical audit was based on the trust prescription
writing
guidelines. This was then used by the pharmacist and
junior medical staff to
conduct three cycles of prospective
clinical audit of the prescription records
of patients admitted
to adult wards at the Caludon Centre. The first audit was
completed
in June 2001, the second in March 2004 and the third in February
2006. Minor adjustments were made to the audit tool in 2004
and the size of
the 2006 audit was increased by the inclusion
of a newly opened ward. Results
were fed back to trust staff
at postgraduate medical education meetings. The
pharmacist
also conducted regular review of the prescription charts on
the
wards between the audits and highlighted errors to the
appropriate medical
team.

Results
A total of 1466 prescriptions on 242 prescription charts were
reviewed
during the three cycles of audit, 67 records in 2001,
57 in 2004 and 118 in
2006. The recording of patient information
on prescription charts improved
after the first cycle of audit
but declined after the second
(
Table 1). Although overall
legibility
improved, the recording of drug allergies, section 58 status
and
age remained especially poor throughout the audit period.
The quality of regular prescriptions showed a consistent improvement over
the audit period (Table 2).
Prescription cancellations improved over the audit period, but the recording
of frequency to be given remained poor.
The overall quality of as required prescriptions also showed
consistent improvement (Table
3). Recording of reason for administration improved, as did
prescription cancellations.

Discussion
The results of this study suggest that clinical audit and feedback
combined
with pharmacist intervention at ward level can improve
the quality of
prescriptions in an in-patient setting. The
overall legibility of
prescriptions reviewed improved to a
point where 99.5% of all prescriptions
reviewed were considered
legible. Specific aspects of prescription writing
that had
been poor in 2001 also showed improvement, most noticeably the
proper
cancelling of as required and regular
prescriptions. However,
some basic aspects of prescription
writing, such as using block capitals for
drug names, only
improved slightly and the recording of drug allergies
remained
very poor throughout the audit period. This is a cause for concern,
although the actual risk it represents is difficult to assess.
Although drug
allergies are believed to occur in 14–17%
of all patients, the most
common are to antibiotics and non-steroidal
anti-inflammatory drugs
(
Vervloet & Durham, 1998),
both
of which are not widely prescribed in our unit. However, recording
drug
allergies remains the responsibility of the prescriber
and other audits have
shown allergy recording rates of 75%
or more are achievable
(
Tuthill et al,
2004).
Continuous quality assurance requires ongoing data collection, review of
that data and action. Various strategies have been suggested to improve the
quality and safety of hospital prescribing, including systems analysis
(Hronek & Bleich, 2002),
electronic prescribing systems (Fowlie
et al, 2000) and applying human error theory
(Dean et al, 2000).
Barber et al (2003)
advocate a three-part strategy aimed at reducing prescribing errors. This is
based on improving individual prescribers competence, controlling the
prescribing environment and changing organisational culture to allow open
discussion of errors. Clinical pharmacists can have a positive impact on
prescribing practice, outcomes and resource use
(Finley et al, 2003),
and we believe that clinical pharmacist review on the wards was the most
effective element of this audit. Medicines are given because it is believed
that the benefits will outweigh any associated risks, but trusts need
appropriate controls to ensure that these risks are minimised
(Healthcare Commission, 2007).
The involvement of clinical pharmacy staff in caring for in-patients is a
service that provides such controls and safety measures.

Acknowledgments
We thank Drs Padmapriya Musunuri and Karthik Modem for help
with data
collection.

References
- BARBER, N., RAWLINS, M. & DEAN FRANKLIN, B. (2003)
Reducing prescribing error: competence, control and culture.
Quality and Safety in Healthcare,
12, 129
–132.[CrossRef]
- DEAN, B., BARBER, N., SCACHTER, M., et al
(2000) Prescribing errors in hospital inpatients: why do they
occur? Pharmaceutical Journal,
265, 17.
- FINLEY, P., CRIMSON, L. & RUSH, J. (2003)
Evaluating the impact of pharmacists in mental health: a systematic review.
Pharmacotherapy, 23, 1634
–1644.[CrossRef][Medline]
- FOWLIE, F., BENNIE, M., JARDINE, G., et al
(2000) Evaluation of an electronic prescribing and administration
system in a British hospital. Pharmaceutical Journal,
265, 16.
- HEALTHCARE COMMISSION (2007) Talking about medicines: The
management of medicines in trusts providing mental health services.
http://www.healthcarecommission.org.uk/_db/_documents/Talking_about_medicines_mental_health_trust_report_200701113216.pdf
- HRONEK, C. & BLEICH, M. (2002) The less than
perfect medication system: a systems approach to improvement.
Journal of Nursing Care Quality,
16, 17
–22.[Medline]
- NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE (2002)
Principles for Best Practice in Clinical Audit.
Radcliffe Medical Press.
- NIRODI, A. & MITCHELL, A. (2002) The quality of
psychotropic drug prescribing in patients in psychiatric units for the
elderly. Aging and Mental Health,
6, 191
–196.[CrossRef][Medline]
- TUTHILL, A., WOOD, K. & CAVELL, G. (2004) An audit
of drug allergy documentation on inpatient drug charts. Pharmacy
World and Science, 26, a48
.
- VERVLOET, D. & DURHAM, S. (1998) Adverse drug
reactions. BMJ, 316, 1511
–1514.[Free Full Text]
Related articles in The Psychiatrist:
- Improving prescription quality in an in-patient mental health unit
- Brian Hallahan, Ivan Murray, and Colm McDonald
The Psychiatrist 2007 31: 435.
[Full Text]