Hostname: page-component-8448b6f56d-mp689 Total loading time: 0 Render date: 2024-04-16T11:50:19.975Z Has data issue: false hasContentIssue false

Choice of antidepressants by psychiatrists working with old people

Published online by Cambridge University Press:  02 January 2018

John Wattis
Affiliation:
Bridge House, Balm Road, Leeds LS10 2TP
Peter Bentham
Affiliation:
Queen Elizabeth Hospital, Birmingham, B15 2Q2
John Bestley
Affiliation:
Yorkshire Training Scheme
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

In 1992, 46 consultants in old age psychiatry were asked to list their five most frequently used antidepressants, with reasons for their choices, and to comment on an information set for evaluating an antidepressant for use in older people. Lofepramine tied with dothiepin as the most popular antidepressant. The relatively new selective serotonin reuptake inhibitors (SSRis) were also widely used. Cardiovascular safety, lack of anticholinergic side effects and safety in overdose were important factors in choice. Some antidepressants were preferred for particular symptoms or circumstances. A modified information set for evaluating an antidepressant for use in older people is presented.

Type
Original papers
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © Royal College of Psychiatrists, 1994

References

Baldwin, R. & Jolly, D. (1986) The prognosis of depression in old age. British Journal of Psychiatry, 149, 577583.CrossRefGoogle ScholarPubMed
British Association for Psychopharmacology (Chairman: Montgomery, S.A.) (1993) Guidelines for treating depressive illness with antidepressants. Journal of Psychopharmacology, 7, 1923.CrossRefGoogle Scholar
Cameron, O.G., Roose, S.P., Robinson, R.G., Katz, I.R. et al (1990) Perspectives on the relationship between cardiovascular disease and affective disorder - discussion. Journal of Clinical Psychiatry, 51(suppl). 1011.Google Scholar
Committee on the Safety of Medicines (1993) Dystonia and withdrawal symptoms with paroxetine. Current Problems (Pharmacovigilance) 19, 1.Google Scholar
Kerihuel, J.C. & Dreyfus, J.F. (1991) Meta-analysis of the efficacy and tolerability of the tricyclic antidepressant Lofepramine. Journal of International Medical Research, 19, 183201.Google Scholar
Montgomery, S.A., Baldwin, D. & Green, M. (1989) Why do amitriptyline and dothiepin appear to be so dangerous in overdose? Acta Psychiatrica Scandinavica, 80(suppl 1354), 4754.Google Scholar
Murphy, E. (1983) The prognosis of depression in old age. British Journal of Psychiatry, 142, 111119.Google Scholar
Song, F., Freemantle, N., Sheldon, T.A., House, A. et al (1993) Selective serotonin reuptake inhibitors: meta-analysis of efficacy and acceptability. British Medical Journal, 306, 683687.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.