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Choice of neuroleptics in epilepsy

Published online by Cambridge University Press:  02 January 2018

Harry McConnell
Affiliation:
Institute of Psychiatry
Denise Duncan
Affiliation:
Maudsley Hospital, Denmark Hill, London SE5 8AZ
David Taylor*
Affiliation:
Maudsley Hospital, Denmark Hill, London SE5 8AZ
*
Correspondence
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The decision to use a neuroleptic in people with epilepsy (PWE) depends on the nature of the psychosis being treated. In some cases a neuroleptic is not required and an adjustment of the antiepileptic drug therapy may be all that is necessary. Antiepileptic drug therapy itself can cause psychosis and this, as well as other aetiologies, should be considered. The choice of neuroleptic in PWE depends on: the nature of the patient's psychosis, including the temporal relationship with seizures and/or any relationship to antiepileptic drug therapy; the epileptogenicity of the neuroleptic; antiepileptic drugs; the efficacy of the neuroleptic; and individual tolerability of side-effects.

Type
Drug Information Quarterly
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © 1997 The Royal College of Psychiatrists

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