Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-16T21:12:53.455Z Has data issue: false hasContentIssue false

Co-occurrence of Gilbert's syndrome and psychosis

Published online by Cambridge University Press:  02 January 2018

M. S. Elameer
Affiliation:
St David's Hospital Carmarthen, Carmarthenshire, SA31 3HB
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Idiopathic unconjugated hyperbilirubinaemia (Gilbert's syndrome) is a common benign disorder that, when seen in association with psychiatric illnesses, often leads to the inappropriate withholding of psychotropic medication. We describe three cases with Gilbert's syndrome and psychosis in which diagnosis of Gilbert's syndrome was delayed. This led to unnecessary investigations, further relapses and increased admissions to hospital. We emphasise the need for psychiatrists to be more aware of this benign condition.

Type
Original Papers
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © 1998 The Royal College of Psychiatrists

References

Davidson, A. R., Rojas-Beuno, A., Thompson, R. P. H., et al (1975) Reduced caloric intake of nicotinic acid provocation tests in the diagnosis of Gilbert's syndrome. British Medical Journal, ii, 480.Google Scholar
Blanckaert, N. & Fevery, J. (1990) Physiology and pathophysiology of bilirubin metabolism. In Hepatology: A Textbook of Liver Disease (eds Zakim, T. & Boyer, T. D.). pp. 254285. Philadelphia, PA: W. B. Saunders.Google Scholar
Cohen, L. S. & Cohen, D. E. (1992) Lithium induced hyperbilirubinaemia in an adolescent. Journal of Clinical Psychopharmacology, 11, 274275.Google Scholar
Durst, R., Jabtinsky-Rubin, K., Dorevitch, A., et al (1993) Idiopathic unconjugated hyperbilirubinaemia (Gilbert's syndrome) and concurrent psychotropic drug administration. Pharmacopsychiatry, 26, 4952.Google Scholar
Gilbert, A. & Lereboullet, P. (1901) La cholemie simple familiale. Semaine Médicale, 21, 241245.Google Scholar
Loyd, D. W., Tsuang, M. T. & Benge, J. W. (1982) A study of a family with Leopard syndrome. Journal of Clinical Psychiatry, 43, 113116.Google ScholarPubMed
Muller, N., Schiller, P. & Ackenheil, M. (1991) Coincidence of schizophrenia and hyperbilirubinaemia. Pharmacopsychiatry, 24, 225228.Google Scholar
Seig, A., Stich, A., Raedsch, R., et al (1986) Gilbert's syndrome: diagnosis by typical serum bilirubin pattern. Clinical Chimica Acta, 154, 4148.CrossRefGoogle Scholar
Taylor, S. (1984) Gilbert's syndrome as a cause of postoperative jaundice. Anaesthesia, 39, 12221224.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.